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Tag: synaptogenesis

Posted on September 5, 2026 by pervial

PE-22-28 and Neuroplasticity: Preclinical Evidence, Mechanisms, and Limitations

3D scientific rendering of neuronal membrane potassium channels and dendritic synapses involved in neuroplasticity research.

PE-22-28 is a synthetic heptapeptide derived from spadin that selectively inhibits TREK-1 potassium channels. In rodent models, it accelerates hippocampal

Read more PE-22-28 and Neuroplasticity: Preclinical Evidence, Mechanisms, and Limitations

Category: PE-22-28
Tags: KCNK2, neurogenesis, neuroplasticity, PE-22-28, Spadin, synaptogenesis, TREK-1 channel

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